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There’s one particular most important problem of combining antidepressant drugs (SSRI, SNRI, MAOI, TCA/TeCA, NRI/NDRI, SMS/SARI) and psychedelics: serotonin syndrome. This issue is incredibly exceptional but major. Serotonin syndrome happens after you just take remedies that induce higher levels of the chemical serotonin to build up in your body.

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